I've blogged about iROC before and last week I met Olivier Lauzeral, President and GM at DAC. They have EDA software to predict the Soft Error Rate of your IC design. Design For Reliability (DFR) is an emerging trend in EDA, so check out this interesting company if you need to know your SER prior to silicon.
Soft Error Rate prediction software-2012-06-04-15-45-04-jpg